I posted about it in the other thread, but Ristar. Again I'm not certain if a 3D update would be the best idea, but a revival with high-quality graphics and gameplay would be awesome.
Oh my God, high five, seriously. I was thinking the exact same thing. I think it would play well on the Wii too.
I want to see the game Giants remade or maybe have a sequel to it. It was hilarious and jetpacking around blowing stuff up was awesome, the fact you could play as one of three races was awesome too. The multiplayer was also pretty good too, a little unbalanced but that could be fixed.
Freedom Fighters too, its an amazing game and Im pretty sure that they could do some amazing things with the game with a sequel, especially internet wise.
Also, not really an old franchise but I really want a Psychonauts sequel.