FWIW, the dev team behind the last released version of Paranoia (v.4 or 'XP') seems to have accepted a lot of the criticisms of the intrinsic problems of Paraoia, introducing the 'Paranoia but not' 'Straight' game form that encourages reduced lethality, greater player engagement, more complex game environments and allowing the running of campaigns with multiple different player classes including retail staff, vid stars, researchers and rescue workers, all in a complex sci-fi satire of modern media-dominated society.
Personally, it is a hobby of mine to attempt to adapt the extremely streamlined WEG d20 RPG system (intended to encourage rapid and easy play free of complex statistics and rule-juggling) to other environments. My current project is an attempt to adapt it to the Fallout and XCom universes.