I think the consensus is that single-panel comics are alive and well. When done properly they are teh awesome. SMBC is one of my favorite comics. (don't forget
Angry Little Girls, btw).
However if you want to develop a more traditional, story-driven comic I can't imagine using only one panel at a time unless you were some sort of super-genius.
PS You need a "first" button on your site.
PPS "I'm edgy" actually made me snort