Undoubtedly my favourite webcomic ever is Saturday Morning Breakfast Cereal.
I've not added the ones I like to favourites, but I clicked 'random' a few times and came up with this one:
http://www.smbc-comics.com/?db=comics&id=758#comicThe only time it doesn't make me laugh is if it's one of the really conceptual sciencey comics that I don't understand. Any time I GET the jokes, which is maybe 98% of the time, it's hilarious.
I also love the way he tends to pile punchlines on top of punchlines, like when the comic was a guy sat next to a tombstone with the name 'Frank' on it, and he's drinking and saying 'We had some good times though, right Frank?' Then the caption says: 'Me and my buddy Frank love finding tombstones with our name on it then drinking by them and pretending the other one's dead. Or at least, we USED to, until Frank died.'
I've been reading Penny Arcade for the last decade, and it's been going another five more years in front of that, so it's pretty insane.
It's not as much... FUN as it used to be. A lot of their really high-concept stuff like Automata is brilliant, but it just isn't that funny any more, generally speaking.
I'll always read a new one, though.
I also quite liked Super Effective, but it updates so infrequently I don't really like endorsing it.
And lastly, 2002-2004 my brother wrote a webcomic called Stickman Stickman (
http://stickman.qntm.org/comics.php?n=0) which I always really liked although I think he feels like it was shitty these days. I disagree. I think it's pretty funny, and when he starts dealing with bigger storylines down the line I think it gets quite awesome.