At level 20, my loadout normally looks like this, though of course it changes a lot:
1) Void() + Crash() + Purge() - AoE debuff to attack and defence, stun, slow, and damage over time.
2) Cull() + Breach() + Ping() - The heavy-hitter, with Breach() for extra range and Ping() to make it faster.
3) Jaunt() + Mask() - For mobility and extra damage on unmasking.
4) Some kind of weak attack that hits multiple enemies, like Bounce().
As passives, I keep another Crash(), as I like that damage resistance and not being slowed, and Jaunt() for faster Turn() regen, along with a few others I've forgotten. I think I have the one which boosts your health.
For big enemies, like a Man or a Jerk or a YoungLady, I can Void them, Jaunt to a good location for a backstab, then Cull them for >2000 damage. Smaller enemies fall prey to Void and Bounce.