I think what dr. nervioso says gets to something else, 94ssd. A lot of it's going to come down to what feels right to you. If it makes you uncomfortable, examine where the discomfort comes from. If it's uncomfortable because it's forcing you to take yourself and your work somewhere you've never been, that can be a good thing. If, on the other hand, you feel uncomfortable because you'd feel like you're working within a form, medium, or subject that doesn't fit because it's not you or not the right reasons, you may just end up resenting yourself later. If it comes from an authentic place and you approach it in a spirit of openness and honesty, it's worth doing. If not... well, that's really a call only you can make.