Actually, let's see, how many paths can we get from Renee to Clinton...
Zebediah's suggestion of ex-boyfriend's ex-girlfriend's roommate's girlfriend's brother (Angus, Faye, Marten, Claire, Clinton)
Mine of boss's girlfriend's son's girlfriend's brother (Jim, Veronica, Marten, Claire, Clinton)
Ex-coworker's ex-boyfriend's current girlfriend's bother (Padma, Marten, Claire, Clinton)
And now to get ridiculous... Coworker's other job's coworker's girlfriend's boss's girlfriend's employee's brother (Elliot, Wil, Penelope, Dora, Tai, Claire, Clinton)
That last path can be modified to ex-boyfriend's girlfriend's brother, instead of girlfriend's employee's brother, but I wanted to see if I could do one without Marten.
Doing one without Claire will be rather difficult, though - it'd require a connection to either Emily or Ms. Augustus that AFAIK isn't there. Or wait...
Boss's daughter's friend's not-boyfriend. Jim, Sam, Emily, Clinton.