Two things immediately jumped into my mind when i saw this strip for the first time. The first is that the layout of this apartment is familiar from what we've seen of it so far. It is, in fact, close to identical to the layout of the one where Marten, Faye, Claire and Bubbles live. Could Renee and Brun be about to move into either the same building or an identical one in the same neighbourhood?
Secondly, is it me or does the realtor look a lot like Claire? Maybe it is just me but I think that Jeph has, consciously or otherwise, given us a clue about what Claire will look like in a bout 10-20 years time (in-comic, of course).
I've also been thinking about Brun's preference for 'caves'. I wonder if she likes to have something approaching a sensory-deprivation chamber when a meltdown is threatening? The less sensory stimulation, the more mental processing power she can devote to trying to sort out and categorise all the backlog of sensations she's got in her head. It's subtleties about her like this that make her an interesting window onto the lives of people with conditions like hers.