There's this neat thread over here:
http://forums.questionablecontent.net/viewtopic.php?t=7722Where-in two of those three questions were answered. You should check it out. And the third question:
3)Computer inking or by hand...i'd prefer by hand but having done neither tips would be good
Much apprechiation to anyone at all who replies...cos man, do i ever need the help.Honestly, you can and should do whatever the heck you want! Experiment. Try all sorts of media. In fact, in the important early, experimental days of your comic, you may want to rotate media for a while. Every time you try a new technique, it's exciting, helps keep you going, and will improve your artwork tremendously.
There are pros and cons in the different ways you ink (if you're going to ink in the first place!), though, which you may want to consider in the end. If you ink things right on the computer, you don't use any paper and your work can be blown up to any size and retain a high quality of image (you need vectored graphics for that, though). If you ink things wrong on the computer, you get an original file that is only 72 dpi and not fit for print. If you ink by hand on paper, then you get a hardcopy original piece of work that is one of a kind and may some day be worth a lot of money to someone (i.e. it's something you can frame and sell). Ink on paper looks really nice. Computer graphics are eco-friendly and more versitile.
I do a combination of both. I ink on paper with Faber-Castell archival pens, then I scan it into the computer and convert it to paths, doing the final layout in Illustrator. This means I have a nice original that my readers might enjoy seeing in person, and I have a final computer file that I can print the size of
a movie screen.In any case, it's all good.