I'm watching reruns of Laugh-In right now, and getting to the end of the second season. In between the George Wallace jokes (a perfectly good old peoples joke all by itself) are an occasional Spiro Agnew joke, usually some riff on his name.
Of course, Laugh-In was very much a product of its time and deliberately referenced many items from the then-current news. Jokes about Viet Nam, living in the US while Black, Native America, or Female, alternate sexualities, and the sexual revolution itself are all staples on the show, so one has to watch with some care and keep the larger context in mind before reaching for things to throw at the screen.