I wonder how Jeph plans to tackle the whole Let's Play thing. I don't suppose he'll model Samantha's LP videos after some established LPer's already out there, but I feel that direction would be more realistic given that it's what any aspiring Let's Player starts out doing.
Following that, who would Samantha's influences be for making Let's Plays? It would give her a framework for how she makes her videos. I personally hope she doesn't base them on PewDiePie and/or Markiplier (although I like Mark). Maybe a Seananners-type LP would be a good start, since his videos revolves around being silly in video games with friends, and doesn't require over-exaggerating reactions. If it's more like Game Grumps/Two Best Friends, I hope Marigold and Momo join and become an awesome Let's Play group.
It'd be hilarious if she's more like Cr1tiKal, though, especially since he's been expanding his horizons lately.
What's saddening, actually, is that I don't know of many well-established women Let's Players for Samantha to possibly be influenced by. Yogscast Hannah, KittyKatGaming, and Tina Dayton (who's more of a Twitch streamer) are three I know off-hand, but that's three out of the several hundreds of male-run Let's Play channels. Maybe Samantha will lead a revolution of women LPers; gods know we need one. There's just too much of the same out there, and the lack of diversity in the gaming community overall needs to change, really.