I've only used one pick-up line - the other times either I was "picked up", or there was no picking up, just mutual coalescing, usually in environs too loud for lines of the non-powdered form - and it was "So, um, do you like your pizza and can I ask you out?" To which she replied, "Sure." There was an awkward pause, and then she said, "So, before...that wasn't a date?"
So it turns out I actually asked her out 6 weeks after our first date.
To get your arm around a chap or lady next to you: "If you were a pirate, would you have a parrot on this shoulder [gesture to the closer] or this shoulder [gesture to the farther]?"
This one is awesome, and a firm favourite among my friends. (Annoyingly, as they hang around with girls who read Neil Gaiman and listen to indie electronica, it generally works.)