I think that Marten is just sighing over the day, but he could be realizing that he and Dora do get into fights over really insignificant things. Maybe he's trying to decide if it's something that needs to be worked on, or it's just incompatibility. Either way, I don't really think they're the "super cute" couple they were when they first started dating.
Faye is sighing over her loveless but great sex with Sven. She's having the "empty feeling" that comes from relationships like that. Sure, she's with someone, but she feels like she's having to hold back. She can't
love him because that's not the relationship they have.
Penny is obvious. She's lonely, and
probably missing Wil. It's possible she just wants
someone to care about though. Who knows.
Hanners and pintsize are just for lulz.
Also, I think it's funny that the Bianchis are the only ones
actually sleeping. Also funny: they sleep on the same side of the bed.
Everyone keeps calling the college girl a redhead... I must be colorblind but isn't she kind of... blond/light brown? Not that it matters. I just thought redheads usually had red hair (or orange-ish I guess)
Yeah, I agree with you. I thought she was another blond. I can
sorta see how you could call it red, but it's not
red red.
I see that Jeph got tired of the "mystery-girl" plotline and decided to do this rather simple but nice 7-character panel.
Sigh. I wonder if the sighs mean anything, are simple expressions of not being able to sleep (other than Penelope), or ?
Pintsize and Hanners are funny as hell, +Shawn's remix of the scene a few posts ago was funny.
Shawn, let me just say that was pure unhindered genius.
I second this emotion. Top work, Shawn. Flawless, and funny too.
Marten and Dora are having trouble, but it could always get worse...
Like this!

(click to enlarge)
Followed by this!

(click to enlarge)
Now that's drama that would make any soap opera cry. 
(And not any more strange than shipping Dora/Sven, lol)
I loved the strip, and I loved getting it so early in the day. However, this does mean we have to wait longer for the next one...
This is so terrible.
I laughed though so it's totally okay.
Thanks

I almost made it Penny and Hanners for the second one, but Penny's hand ended up over Hanner's mouth. I didn't think that was so great :p . Then I almost made it Dora and Penny (after the Marten/Sven one, which was easy because they're drawn to the same scale) which worked out well because it looked like Penny was holding sleeping Dora, but it wasn't as funny as Dora/Hanners :p